the main purpose of this research is to explanation of self study place and characteristics in elearning content. main question of this research is; What is the position of self- study among the instructional indicators of e-learning and multimedia content. This study was done with using a synthesis method. finding showed; e-learning and multimedia content quality has instructional and technological dimension. self study is is a main part of instructional dimension that must to be considered in design and developing of e-learning content. self study content with applying Self - explanation, Self- contained, Self- directed, Self- motivation and Self- evaluation strategies can pose the learners in various interpretations and reflections positions. self study content has three part including opening section, main body and the final section. with applying open-ended self-explanation prompt,Scaffolded self-explanation prompt,Resource-based self-explanation prompt, Menu-based self-explanation prompt and Focused self-explanation prompt can improve e-learning and multimedia content quality from instructional dimension.